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. 2022 May 5;11(9):1557. doi: 10.3390/cells11091557

Table 4.

Previous and present ANXA11 rs1049550 association studies with sarcoidosis.

Author Year Country Ethnicity Case/Control, N Case T Allele Freq Control T Allele Freq OR, 95% CI, p Value * Population T Allele Frequency gnomAD
Hofmann S et al. [3] 2008 Germany Caucasian 1636/1811 0.33 0.41 0.70, 0.63–0.77, 1 × 10−12 European: 0.42
Li et al. [4] 2010 Germany Caucasian 349/313 0.35 0.45 0.65, 0.52–0.81, 1 × 10−4 European: 0.42
Mrazek et al. [5] 2011 Czech Caucasian 245/254 0.35 0.42 0.77, 0.59–0.99, 0.04 European: 0.42
Levin et al. [6] # 2013 USA European American 446/350 0.36 0.42 0.76, 0.62–0.93, 0.008 European: 0.42
African American 1232/893 0.15 0.18 0.83, 0.70–0.97, 0.02 African/African American: 0.20
Morais et al. [7] 2013 Portugal Caucasian 208/197 0.33 0.45 0.61, 0.46–0.81, 6 × 10−4 European: 0.42
Feng et al. [8] 2014 China Chinese-Han 412/418 0.29 0.40 0.60, 0.49–0.73, 8 × 10−7 East Asian: 0.66 §
Sikorova et al. [9] 2020 Greece Caucasian 103/100 Not available Not available 0.59, 0.39–0.89, 0.01 European: 0.42
Karakaya et al. Netherlands Caucasian 262/363 0.30 0.41 0.61, 0.48–0.77, 3 × 10−5 European: 0.42

* Odds ratio (OR), 95% confidence interval (CI), and p-values are calculated from the data provided in the original articles. # For correct presentation, the C and T allele are switched. § The gnomAD database shows that the T allele in East Asian is the major allele. Within the gnomAD database, the 1 KG shows different East Asian populations: Han Chinese in Beijing have a T allele frequency of 0.6373; Southern Han Chinese have a T allele frequency of 0.6619. The genotype data were not available for the study by Sikorova et al.; values were copied from the original article.