Figure 4.

(A) Frequencies of fixation of weakly deleterious mutations relative to that of neutral mutations for different rates of recombination (r), when there is a potential for interference amongst deleterious mutations and BGS effects are accounted for. Red solid circles show the expected probability calculated by Equation (4) integrating over the interval of $2N_e{s}_d$. (B–G) Effects of sweeps immediately post-fixation for (B–D) Drosophila-like and (E–G) human-like parameters and architecture. Recovery of nucleotide diversity per site ($\pi$) is shown relative to the mean intergenic diversity under BGS (${\pi }_0$), around a recent fixation (shown at position 0 on the x-axis). The target site has experienced a weakly deleterious fixation ($2N{s}_d$ between 1 and 2). Solid lines represent mean values obtained from all substitutions in all replicates, shaded regions correspond to 1 SE above and 1 SE below the mean. Crosses correspond to simulations based on Equation (27) of Tajima (1990) for 2Ns = 0. The extent of BGS in these scenarios is: (B) B = 0.81, (C) B = 0.79, (D) B = 0.67, (E) B = 0.87, (F) B = 0.85, and (G) B = 0.83.