Figure 1.

Nuci prevented obesity in HFD-fed mice. (a) The molecular structure of Nuci. Seven-weeks male C57BL/6J mice were fed with ND, HFD, HFD supplemented with Nuci and HFD with subcutaneous injection of Lira at 200 μg/kg/day for 12 weeks, body weight (b) and energy intake (d) were recorded, and body weight gain (c) was calculated by the end of the experiment. The amount of fat mass (e), including sWAT, eWAT, and pWAT, as well as the weight of BAT (g) and liver (h) were recorded. Fat mass of body weight (f) was calculated by dividing the sum of fat mass by body weight. Data were presented as mean ± SE, n = 12 in each group. * p < 0.05 vs. the HFD group.