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Changes in PK enzyme expression in the early-phase non-alcoholic steatohepatitis (NASH) mouse model. (A) Protein expression levels of PKLR, PKM2, and phosphorylated PKM2 (p-PKM2) in the liver of control and NASH mice after 1, 3, and 9 weeks (n = 3). GAPDH was used as an internal control. (B) Images of each staining. Upper panels, HE; 2nd panels, Sirius Red staining; 3rd panels, PKLR; lower panels, PKM2. Scale bars = 50 µm.
