Table 3.
Antiviral activity of chitosan and its derivatives.
Chitosan | Virus | Cell Line | Concentration | Ref. |
---|---|---|---|---|
Zinc stabilized chitosan | HIV-1 | Human peripheral blood mononuclear | 0.1–0.2% w/v chitosan in acetic acid | [95] |
Curcumin-loaded chitosan nanocomposite | Hepatitis C | human hepatoma | 20 µg/mL curcumin in 4% chitosan composite | [94] |
Chitosan with medium molecular weight | AD169 strain of HCMV | Human embryonic lung fibroblasts | 9–14 mg Fostcanet antiviral drug in 4.5 mg chitosan |
[98] |
Silver-loaded chitosan | H1N1 Influenza A | Madin-Darby canine kidney | Ag NPs in 10 mg/mL chitosan | [99] |
Nanosilver-loaded polyquaternary phosphonium oligochitosan | Hepatitis A | Vero | 100 µL/mL silver NPs | [100] |
3,6-O-sulfated chitosan | HPV | 293FT, Hela, HaCaT | 2.4, 4.7, 4.2 µg/mL chitosan | [101] |
HTCC | SARS-CoV2 | human airway epithelium (HAE) | 12.5 µg/mL HTCC | [96] |
GCPQ | SARS-CoV2 | Vero E6 and A549 | 10 µg/mL GCPQ | [97] |