Table 7.
List of studies on antiviral activity of sialyl-based polymers with their mechanism of action.
Sialyl-Based Polymers | Virus | Cell Line | Mechanism of Action | Ref. |
---|---|---|---|---|
Amide-sialoside protein conjugates | IAV | H1N1, H3N2, H9N2 | Binding to the virus and inhibiting replication | [157] |
Thiosialoside-modified poly (methyl vinyl ether-alt-maleic anhydride) | IAV | MDCK | inhibiting both early attachment and late release during viral infection | [160] |
silyl oligosaccharides modified glycopolymers | IAV | H1N1 | Binding with hemagglutinin on viral surface | [161] |
Bioinspired brush polymers containing α-2,6-linked sialic acid | IAV | H1N1 | binding hemagglutination on viral surface | [163] |