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. 2022 Apr 28;27(9):2811. doi: 10.3390/molecules27092811

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Hemolysis assay microtubes after incubation with nanoparticles suspensions in different concentrations (1, 10, 25, 50, 75 and 100 µM) for 1 hour and centrifugation at 1500 G for 5 min. PC (Positive Control, distilled water), NC (Negative Control, saline), UnNPs (Unloaded Nanoparticles), LdCurNPs (L-DOPA and Curcumin- Loaded Nanoparticles). (B,C) The results presented are mean ± standard error of the hemolysis rate of samples 1 and 2, respectively. Dotted lines are the thresholds of 5% (slightly hemolytic) and 2% (non-hemolytic) hemolysis rate and * p < 0.05; n.s. p > 0.05 when compared with the negative control.