. 2022 Apr 29;14(9):1873. doi: 10.3390/nu14091873

Table 2.

Multivariate analysis of questionnaire items and associated clinical markers.

Questionnaire Item	Clinical Variable	N	Estimated Slope	SE	p-Value
Section 1: Dizziness
1. Dizziness score	Glucose	264	−0.075	0.032	0.018
	Low insulin	117	0.600	0.227	0.008
	Proximal Femur BMD Z-score	302	−0.196	0.063	0.002
	High cortisol:insulin ratio	95	0.513	0.219	0.019
Section 2: Gastrointestinal Score
2. Gastrointestinal score	AP Spine BMD Z-score	304	−0.136	0.0394	0.004
2. Gastrointestinal score	Proximal Femur Z-score	302	−0.078	0.039	0.046
Section 3: Thermoregulation- no findings
Section 4: Injury and illness
4A How many acute injuries?	Low T₃	177	0.683	0.279	0.014
4A How many acute injuries?	T₃	177	−0.140	0.059	0.019
4B How many overload injuries?	Low T₃	177	0.537	0.230	0.020
	T₃	177	−0.130	0.054	0.018
	High cortisol	207	0.391	0.190	0.039
	High cortisol:insulin ratio	95	0.506	0.238	0.034
4D How many breaks in training have you had for acute injury?	High cortisol	209	0.389	0.168	0.021
	Cortisol	209	22.725	9.856	0.022
4F Number of days unable to train due to illness	Low T₃	176	0.762	0.267	0.004
4F Number of days unable to train due to illness	T₃	176	−0.191	0.054	0.001
4 Injury and illness score	Low T₃	177	0.173	0.065	0.008
	T₃	177	−0.038	0.014	0.008
	High cortisol	217	0.093	0.045	0.040
Section 5: Wellbeing and recovery
5A Fatigue sub score	Total cholesterol	241	0.048	0.022	0.028
5D Poor recovery sub score	Total cholesterol	241	0.078	0.031	0.013
5E Low energy levels	Low insulin	117	0.2133	0.098	0.030
5 Poor wellbeing score	Total cholesterol	241	0.016	0.006	0.013
Section 6: Sex Drive
6A How would you rate your sex drive in general?	High cortisol:insulin ratio	95	0.767	0.373	0.039
	Weight flux	115	1.908	0.579	0.001
	Training amount	114	7.995	4.010	0.049
	Low insulin	95	1.177	0.416	0.005
	Cortisol:insulin ratio	95	4.959	1.897	0.011
	Total Testosterone	115	−1.882	0.826	0.025
	Proximal femur BMD Z-score	112	−0.326	0.130	0.014
	T₃	114	−0.195	0.090	0.033
6B How would you rate it over the last month compared to normal?	T₃	114	−0.221	0.106	0.039
	Glucose	107	−0.172	0.077	0.027
	Low insulin	95	0.817	0.398	0.040
6C How often would you wake with a morning erection?	AP Spine BMD Z-score	115	−0.177	0.074	0.019
	Training amount	114	4.734	2.265	0.039
	Low free testosterone:cortisol ratio	114	0.4346	0.1946	0.026
	Proximal femur BMD Z-score	112	−0.228	0.073	0.002
	Low BMD	115	0.520	0.211	0.014
6D Over the last month how does the number of morning erections compare to normal for you?	Low RMR_ratio	115	0.743	0.343	0.030
Low sex drive score	High cortisol:insulin ratio	95	0.206	0.103	0.045
	Weight flux	115	0.4819	0.180	0.009
	Low insulin	95	0.209	0.105	0.045
	Proximal femur BMD Z-score	112	−0.121	0.039	0.003
	Testosterone	115	−0.5874	0.2527	0.022
	T₃	114	−0.074	0.028	0.009
Exercise Hypogonadal Male Condition	Weight flux	118	2.049	0.887	0.023
Exercise Hypogonadal Male Condition	Proximal femur BMD Z-score	115	−0.397	0.193	0.042

Significance set at p < 0.05, n = 310. “High” represents the top and “low” represents the bottom quartile of the test locations’ clinical variables, respectively.