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. 2022 Apr 27;11(9):1178. doi: 10.3390/plants11091178

Table 1.

Summary of homologs of cannabis genes used in qPCR.

Gene Function PAMP Reference
Ethylene Response Factor 1
[ERF1]
Transcriptional activator which acts downstream of the ethylene signaling pathway. It mediates development and regulates pathogen defense genes [16]. harpin and flg22 [2,17]
Ethylene Insensitive Protein 5
[EIN5]
Required for plant growth enhancement [2]. Acts downstream of CTR1, a negative regulator of the pathway. If ethylene is present, CTR1 does not act, and the pathway can be activated [3]. harpin [3]
Ethylene Insensitive Protein 2
[EIN2]
Required for insect resistance in plants [2]. Protein located downstream of CTR1 in the ethylene pathway. If CTR1 is inhibited, then EIN2 may be activated. It is a Nramp-like protein, meaning it is a natural resistance-associated macrophage protein [18]. harpin [2,18]
Flg22-Induced
Receptor Like Kinase 1
[FRK1]
Associated with early defense signaling as well as mediating senescence. Following flg22 exposure in an organism, FRK1 regulation likely increases accordingly [19]. flg22 [19]
Pathogenesis Related Protein 1
[PR1]
Gene expression increases following pathogen detection [20]. It is an indicator of systemic acquired resistance. flg22 [21]