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. 2022 Apr 23;23(9):4664. doi: 10.3390/ijms23094664

Figure 5.

Figure 5

Overview of IgG Fc glycosylation signatures of idiopathic membranous nephropathy (IMN) and other nephropathies that are different from IMN (PN), compared in both cases to healthy controls. The p-values are given for seven N-glycosylation traits of serum IgG1, 2, and 4. Significant differences (p < 0.05) are highlighted in bold and colored based on the direction of the difference (green for lower values and red for higher values in disease vs. control). The IMN patients were used all together (IMN) or based on PLA2R titer (HighPLA2R if > 999; Low PLA2R if < 999). For the comparisons, sex- and age-matching with healthy controls were performed based on the clustered and one-to-one approach.