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. 2022 May 9;27(9):3039. doi: 10.3390/molecules27093039

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of DFO administration on infarcted area in hearts isolated from vehicle- or BC-treated rats. Infarct size was measured in hearts (n = 4 in each group) after 120 min of REP by perfusing the hearts with triphenyl-tetrazolium-chloride (TTC) solution, followed by macroscopic analysis of transverse sections of each heart. Data are expressed as average size (%) of infarcted area ± SEM for each group. * p < 0.05 in comparison with the values for hearts from vehicle-treated control rats. Representative pictures are also shown under the bars. White areas indicate infarcted tissues using triphenyltetrazolium chloride staining, whereas red color represents the survival regions. C: vehicle-treated control group; DFO: vehicle-treated, DFO-administered group; BC: BC-treated group without DFO administration; BC + DFO: BC-treated group with DFO administration.