Table 2.
AST, ALT, and AST/ALT ratio distribution among Hiroshima residents who had abdominal ultrasonography during check-up
| N | AST (IU/L) | ALT (IU/L) | AST/ALT (AAR) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean ± SD | Median | Min–max | AST ≥ 30 IU/L (%) | Mean ± SD | Median | Min–max | ALT ≥ 30 IU/L (%) | Mean ± SD | Median | Min–max | ALT/ALT > 1.0 (%) | ||
| Total population who received ultrasonography | 5999 | 23.4 ± 12.0 | 21 | 8–363 | 15.4% | 26.2 ± 20.6 | 20 | 2–503 | 26.5% | 1.06 ± 0.39 | 1.0 | 0.26–7 | 47.8% |
| Non-drinkers without fatty liver | 3781 | 20.9 ± 9.8* | 19 | 8–363 | 7.6%# | 20.6 ± 14.6* | 18 | 2–503 | 13.4%# | 1.15 ± 0.39* | 1.1 | 0.26–7 | 60.0%# |
| Non-drinkers with fatty liver (NAFLD) | 1399 | 28.0 ± 13.6* | 25 | 11–167 | 30.8%# | 40.7 ± 26.2* | 33 | 7–291 | 59.4%# | 0.78 ± 0.26* | 0.73 | 0.34–2.47 | 14.8%# |
| p value | < 0.0001* | < 0.0001# | < 0.0001* | < 0.0001# | < 0.0001* | < 0.0001# | |||||||
AST alanine aminotransferase, ALT asparate aminotransferase, AAR AST/ALT ratio, SD standard deviation, NAFLD non-alcoholic fatty liver disease;
*p value of the Wilcoxon test comparing the AST and ALT levels and AST/ALT ratios in non-drinkers without fatty liver and non-drinkers with fatty liver (NAFLD)
#p value of the Chi-square test comparing the percentage of AST ≥ 30 IU/L, ALT ≥ 30 IU/L, and ALT/ALT > 1.0 in non-drinkers without fatty liver and non-drinkers with fatty liver (NAFLD)