Figure 2.
Representative results of CRC case showing dMMR-IHC and MSI-H by PCR. (A) MMR-IHC results: intact expression of MLH1 and PMS2 in tumor cells (original magnification 10×); loss expression of MSH2 and MSH6 in tumor cells with positive internal control (original magnification 10×). (B) MSI-PCR results: stability of NR21, NR22 and MONO27; instability of BAT25, BAT26, NR21, NR24, NR27 and CAT25 (red lines indicate samples while blue lines indicate MSS controls).
