Table 3.

Examples of polymer-based nanosystems for spinal cord delivery.

Nanocarrier Material	Cargo	Characteristics	Refs.
PLGA	ChABC enzyme	Morphology: nanospheres Average size: 273.5 ± 36.4 nm	[49]
PLGA	Superoxide dismutase Catalase	Morphology: circular structures Average size: 122 ± 5.5 nm	[23]
PLA	Docosahexaenoic acid	Morphology: core-shell nanofibers Average core diameter: 300 nm Average shell thickness: 80 nm	[50]
PEG/PPG/PEG	Zonisamide	Morphology: almost spherical nanomicelles Average size: 105 nm	[51]
Stearic acid-chitosan	Sesamol	Morphology: spherical nanomicelles Hydrodynamic radius without loading: 53.12 ± 6.21 nm Hydrodynamic radius with loading: 59.12 ± 7.31 nm	[52]
Chitosan	CeO2 nanoparticles	Morphology: core-shell nanospheres Average size: 15–25 nm	[53]