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. 2022 May 5;23(9):5177. doi: 10.3390/ijms23095177

Table 4.

Isoflavones: Table showing the experimental method (type of nerve injury and animal model), the dose, and method of administration of genistein.

Genistein
Ref. Type of Nerve Lesion and Animal Model Type of Administration/Experimental Groups
Ozbek et al., 2017 [70] Sciatic nerve crush injury or end-to-end repair;
male Sprague Dawley rats
  • -

    Sham (no injury);

  • -

    Control (crush injury);

  • -

    Crush injury + 20 mg/kg genistein;

  • -

    Crush injury + 90 mg/kg gabapentin;

  • -

    End-to-end repair + 20 mg/kg genistein;

  • -

    End-to-end repair + 90 mg/kg gabapentin.

Genistein and gabapentin (control) were administered intraperitoneally for 30 days.