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. 2022 Apr 21;23(9):4583. doi: 10.3390/ijms23094583

Figure 1.

Figure 1

Figure 1

HGD and GSTZ1 are down-regulated and associated with prognosis in KIRC. (A) The tyrosine-metabolizing enzymes (TAT, HPD, HGD, GSTZ1, and FAH) mRNA expression levels between tumor and normal tissues in patients with RCC in TGCA database. (B) Overall survival of patients with RCC grouped by tyrosine-metabolizing enzymes’ expression through GEPIA web server. (C) The tyrosine-metabolizing enzymes (HGD and GSTZ1) protein expression levels between tumor and normal tissues in patients with KIRC in TGCA database. (D) The types and frequency of mutations of VHL, HGD and GSTZ1 in RCC patients.