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HGD/GSTZ1 promotes the conversion of glucose to lactate in KIRC. (A,B) GSEA pathway enrichment analyses of the key regulator (GOT1, GOT2, HGD, and GSTZ1) signature in patients with RCC from the TCGA datasets. (C) The glucose-metabolizing enzymes mRNA expression levels between tumor and normal tissues in patients with KIRC in TGCA database. (D) Schematic diagram of the glucose metabolism pathway.
