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. 2022 Apr 21;23(9):4583. doi: 10.3390/ijms23094583

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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HGD/GSTZ1 promotes cell cycle and tumor progression. (A–C) GSEA pathway enrichment analyses of key regulator (HGD, GSTZ1, GOT1, GOT2, SLC2A1, and LDHA) signature in patients with RCC from the TCGA datasets. (D) The overlapping analysis for related genes of cell cycle in RCC patients. The number represents the number of genes shared by different gene sets. (E) The correlation analysis between HGD/GSTZ1/GOT1/GOT2/prognosis and cell cycle related target genes. (F) The cell cycle related key target genes mRNA expression levels between tumor and normal tissues in patients with KIRC in TGCA database.