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. 2022 May 13;3:50. doi: 10.1186/s43058-022-00281-7

Table 2.

Study outcomes for the evidence-based intervention

Implementation science terminology Definition Study terminology
Evidence-based intervention Evidence-based interventions are supported by research that has established a causal relationship between the intervention and a specified improvement in individual- or population-level health behaviors, health outcomes, or health-related environments [20]. Evidence-based chemotherapy for advanced-stage Kaposi’s sarcoma
Primary implementation outcomes - intervention
Implementation science terminology Definition Study terminology Level of evaluation Outcome measures
Service Penetration The number of eligible persons who use a service, divided by the total number of persons eligible for the service [19]. Chemotherapy initiation Individual level (person with KS) Cumulative incidence of receiving the first dose of chemotherapy after KS diagnosis accounting for death as a competing event.
Fidelity The degree to which an intervention was implemented as it was prescribed in the original protocol or as it was intended by the program developers [19]. Chemotherapy completion Individual level (person with KS) Cumulative incidence of chemotherapy completion, defined as completing >6 cycles of chemotherapy, completing all cycles recommended by the provider (occasionally <6), or the person with KS completing the prescribed number of cycles up until a provider-driven regimen change, accounting for death as a competing event.
Secondary service outcomes—intervention
Timeliness The reduction of waits and harmful delays for both those who receive and those who give care [21]. Time to oncology consultation Individual level (person with KS) Time in days from when the biopsy result is given to the person with KS to the first oncology consultation
Secondary client and health outcomes—intervention
Mortality Individual level (person with KS) Cumulative incidence of death
Quality of Life Individual level (person with KS) Total Score Quality of Life (Medical Outcomes Study HIV Health Study) [22]
Stigma Individual level (person with KS) Total Score Stigma (Abridged Berger HIV Stigma Scale) [23]
Social Support Individual level (person with KS) Total Score Social Support (MSPSS) [22]