Implementation science terminology |
Definition |
Study terminology |
Evidence-based intervention |
Evidence-based interventions are supported by research that has established a causal relationship between the intervention and a specified improvement in individual- or population-level health behaviors, health outcomes, or health-related environments [20]. |
Evidence-based chemotherapy for advanced-stage Kaposi’s sarcoma |
Primary implementation outcomes - intervention |
Implementation science terminology |
Definition |
Study terminology |
Level of evaluation |
Outcome measures |
Service Penetration |
The number of eligible persons who use a service, divided by the total number of persons eligible for the service [19]. |
Chemotherapy initiation |
Individual level (person with KS) |
Cumulative incidence of receiving the first dose of chemotherapy after KS diagnosis accounting for death as a competing event. |
Fidelity |
The degree to which an intervention was implemented as it was prescribed in the original protocol or as it was intended by the program developers [19]. |
Chemotherapy completion |
Individual level (person with KS) |
Cumulative incidence of chemotherapy completion, defined as completing >6 cycles of chemotherapy, completing all cycles recommended by the provider (occasionally <6), or the person with KS completing the prescribed number of cycles up until a provider-driven regimen change, accounting for death as a competing event. |
Secondary service outcomes—intervention |
Timeliness |
The reduction of waits and harmful delays for both those who receive and those who give care [21]. |
Time to oncology consultation |
Individual level (person with KS) |
Time in days from when the biopsy result is given to the person with KS to the first oncology consultation |
Secondary client and health outcomes—intervention |
|
Mortality |
Individual level (person with KS) |
Cumulative incidence of death |
Quality of Life |
Individual level (person with KS) |
Total Score Quality of Life (Medical Outcomes Study HIV Health Study) [22] |
Stigma |
Individual level (person with KS) |
Total Score Stigma (Abridged Berger HIV Stigma Scale) [23] |
Social Support |
Individual level (person with KS) |
Total Score Social Support (MSPSS) [22] |