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. 2022 May 4;11(9):1541. doi: 10.3390/cells11091541

Figure 4.

Figure 4

Disease activity index and morphological changes in DSS-induced colitis. (A) Disease activity index (DAI) of wildtype (wt) and intestinal MD3-overexpressing mice (MD3-OE) during DSS-induced colitis (*** p < 0.001; n = 11–12). (B) Length and width changes in colons of wt and MD3-OE occurred in the same manner during DSS-induced colitis (*** p < 0.001; n = 11–12). (C) Representative H&E stainings of colons from wt and MD3-OE mice. Notable was that in about one third of the MD3-OE mice the colon appeared to be impaired only minimally (representative image on the right; bar = 200 µm).