Table 4.
Statistically significant correlation coefficient in whole group of PCOS women between BMI, WHR, glucose metabolism and lipid profile parameters and selected hormone concentrations with SOD1 activity and Zn and Cu concentrations.
| Correlation | SOD1 Activity [U/L] | Cu [µg/L] | Zn [µg/L] |
|---|---|---|---|
| BMI [kg/m2] | −0.27; 0.041 | 0.42; <0.001 | NS |
| WHR | −0.33; 0.020 | 0.36; 0.005 | NS |
| Fasting glucose [mg/dL] | NS | NS | 0.30; 0.010 |
| Fasting insulin [uIU/mL] | NS | 0.26; 0.024 | NS |
| Glucose after OGTT [mg/dL] | −0.27; 0.043; | NS | NS |
| Insulin after OGTT [uIU/mL] | −0.34; 0.011 | 0.23; 0.049 | NS |
| HOMA-IR | NS | 0.28; 0.016 | NS |
| Triglycerides [mg/dL] | −0.36; 0.007 | 0.36; 0.002 | NS |
| LH [lU/L] | −0.28; 0.041 | NS | NS |
| FSH [lU/L] | NS | NS | NS |
| FT4 [ng/dL] | −0.30; 0.026 | NS | NS |
| TSH [mU/L] | −0.33; 0.010 | NS | NS |
| SHBG [nmol/L] | NS | −0.30; 0.011 | NS |
| Total testosterone [ng/mL] | NS | NS | NS |
| Free testosterone [pg/mL] | NS | NS | NS |
| Androstenedione [ng/mL] | NS | NS | NS |
| 17-β-E2 [pg/mL] | NS | NS | NS |
| 17-OHP [nmol/L] | NS | NS | NS |
Legend: Values shown as median (1st quartile, 3rd quartile); PCOS—polycystic ovary syndrome; SOD—superoxide dismutase; Zn—zinc; Cu—copper; LH—luteinizing hormone; FSH—follicle-stimulating hormone; FT4—free thyroxine; TSH—thyrotropin; SHBG—sex hormone-binding globulin; 17-β-E2—17-β -estradiol; 17-OHP—17-α-hydroxyprogesterone; NS—not significant.