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. 2022 Apr 27;27(9):2780. doi: 10.3390/molecules27092780
AChE Acetylcholinesterase
AD Alzheimer’s Disease
ago-PAM Allosteric Agonist And Positive Allosteric Modulator
ALS Amyotrophic Lateral Sclerosis
AMPARs α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid-Type Glutamate Receptors
Arc Activity-Regulated Cytoskeleton-Associated Protein
ASC Apoptosis-Associated Speck-Like Protein Containing A Caspase Recruitment Domain
Amyloid-β
BAMs Border-Associated Macrophages
BDNF Brain-Derived Neurotrophic Factor
CaM Calmodulin
CaMKII CaM-Binding Protein Kinase II
ChAT Choline Acetyltransferase
CNS Central Nervous System
CREB cAMP Responsive Element-Binding Protein
CSF1R Colony-Stimulating Factor 1 Receptor
Cytob558 Cytochrome B558
DAM Disease-Associated Microglia
DAMPs Damage-Associated Molecular Patterns
EAE Experimental Autoimmune Encephalomyelitis
ER Endoplasmic Reticulum
Erk1/2 Extracellular Signal-Regulated Kinase 1/2
FACS Fluorescence-Activated Cell Sorting
GSDMD Gasdermin D
HABs High-Affinity Binders
HDAC1 Histone Deacetylase 1
HO-1 Heme Oxygenase-1
Iba-1 Ionized Calcium-Binding Adaptor Molecule-1
IFN-γ Interferon-γ
IGF-1 Insulin-Like Growth Factor-1
IL Interleukin
iNOS Inducible Nitric Oxide Synthase
KD Knockdown
KO Knockout
LABs Low-Affinity Binders
LPS Lipopolysaccharide
LSP Lipopolysaccharide
LTP Long-Term Potentiation
MABs Mixed-Affinity Binders
MAPKs Mitogen-Activated Protein Kinases
miRNA microRNA
MPTP Mitochondrial Permeability Transition Pore
MRI Magnetic Resonance Imaging
MS Multiple Sclerosis
nAChRs Nicotinic Acetylcholine Receptors
NAMPs Neurodegeneration-Associated Molecular Patterns
NLRP3 NOD-, LRR-, And Pyrin Domain Containing 3
NOX2 NADPH Oxidase 2
NQO1 NAD(P)H: Quinone Oxidoreductase-1
P2Y12R P2Y12 Receptor
PAMs Positive Allosteric Modulators
PAMPs Pathogen-Associated Molecular Patterns
PBR Peripheral-Type Benzodiazepine Receptor
PD Parkinson’s Disease
PET Positron Emission Tomography
PI3K Phosphatidylinositol 3 Kinase
PRRs Pattern Recognition Receptors
Rac1 Ras-Related C3 Botulinum Toxin Substrate 1
RIC-3 Resistance To Inhibitors Of Cholinesterase-3
ROS Reactive Oxygen Species
scRNA-seq Single Cell RNA-Sequencing
SIRT1 Sirtuin 1
SNP Single Nucleotide Polymorphism
snRNA-seq Single Nucleus RNA- Sequencing
SPECT Single Photon Emission Computed Tomography
TNF Tumor Necrosis Factor
TSPO Translocator Protein
TXNRD1 Thioredoxin Reductase
WAVE Wiskott–Aldrich Syndrome Protein Family Verprolin-Homologous Protein
σ1-R σ1 Receptor