| AChE | Acetylcholinesterase |
| AD | Alzheimer’s Disease |
| ago-PAM | Allosteric Agonist And Positive Allosteric Modulator |
| ALS | Amyotrophic Lateral Sclerosis |
| AMPARs | α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid-Type Glutamate Receptors |
| Arc | Activity-Regulated Cytoskeleton-Associated Protein |
| ASC | Apoptosis-Associated Speck-Like Protein Containing A Caspase Recruitment Domain |
| Aβ | Amyloid-β |
| BAMs | Border-Associated Macrophages |
| BDNF | Brain-Derived Neurotrophic Factor |
| CaM | Calmodulin |
| CaMKII | CaM-Binding Protein Kinase II |
| ChAT | Choline Acetyltransferase |
| CNS | Central Nervous System |
| CREB | cAMP Responsive Element-Binding Protein |
| CSF1R | Colony-Stimulating Factor 1 Receptor |
| Cytob558 | Cytochrome B558 |
| DAM | Disease-Associated Microglia |
| DAMPs | Damage-Associated Molecular Patterns |
| EAE | Experimental Autoimmune Encephalomyelitis |
| ER | Endoplasmic Reticulum |
| Erk1/2 | Extracellular Signal-Regulated Kinase 1/2 |
| FACS | Fluorescence-Activated Cell Sorting |
| GSDMD | Gasdermin D |
| HABs | High-Affinity Binders |
| HDAC1 | Histone Deacetylase 1 |
| HO-1 | Heme Oxygenase-1 |
| Iba-1 | Ionized Calcium-Binding Adaptor Molecule-1 |
| IFN-γ | Interferon-γ |
| IGF-1 | Insulin-Like Growth Factor-1 |
| IL | Interleukin |
| iNOS | Inducible Nitric Oxide Synthase |
| KD | Knockdown |
| KO | Knockout |
| LABs | Low-Affinity Binders |
| LPS | Lipopolysaccharide |
| LSP | Lipopolysaccharide |
| LTP | Long-Term Potentiation |
| MABs | Mixed-Affinity Binders |
| MAPKs | Mitogen-Activated Protein Kinases |
| miRNA | microRNA |
| MPTP | Mitochondrial Permeability Transition Pore |
| MRI | Magnetic Resonance Imaging |
| MS | Multiple Sclerosis |
| nAChRs | Nicotinic Acetylcholine Receptors |
| NAMPs | Neurodegeneration-Associated Molecular Patterns |
| NLRP3 | NOD-, LRR-, And Pyrin Domain Containing 3 |
| NOX2 | NADPH Oxidase 2 |
| NQO1 | NAD(P)H: Quinone Oxidoreductase-1 |
| P2Y12R | P2Y12 Receptor |
| PAMs | Positive Allosteric Modulators |
| PAMPs | Pathogen-Associated Molecular Patterns |
| PBR | Peripheral-Type Benzodiazepine Receptor |
| PD | Parkinson’s Disease |
| PET | Positron Emission Tomography |
| PI3K | Phosphatidylinositol 3 Kinase |
| PRRs | Pattern Recognition Receptors |
| Rac1 | Ras-Related C3 Botulinum Toxin Substrate 1 |
| RIC-3 | Resistance To Inhibitors Of Cholinesterase-3 |
| ROS | Reactive Oxygen Species |
| scRNA-seq | Single Cell RNA-Sequencing |
| SIRT1 | Sirtuin 1 |
| SNP | Single Nucleotide Polymorphism |
| snRNA-seq | Single Nucleus RNA- Sequencing |
| SPECT | Single Photon Emission Computed Tomography |
| TNF | Tumor Necrosis Factor |
| TSPO | Translocator Protein |
| TXNRD1 | Thioredoxin Reductase |
| WAVE | Wiskott–Aldrich Syndrome Protein Family Verprolin-Homologous Protein |
| σ1-R | σ1 Receptor |