Skip to main content
. 2022 Apr 8;36(5):e24408. doi: 10.1002/jcla.24408

FIGURE 3.

FIGURE 3

MiR‐486‐3p was sponged by circ_0011298. A, The expression of miR‐486‐3p and miR‐616 (potential target miRNAs of circ_0011298) was determined in normal, Taxol‐sensitive NSCLC, and Taxol‐resistant NSCLC tissues. B, The putative binding sites of miR‐486‐3p and circ_0011298 were exhibited. C, MiR‐486‐3p expression was measured in Taxol‐resistant NSCLC cells introduced with miR‐NC, miR‐486‐3p, anti‐NC, or anti‐miR‐486‐3p. D and E, Taxol‐resistant NSCLC cells were co‐introduced with circ_0011298 WT/MUT and miR‐NC/miR‐486‐3p, and the luciferase activity was detected. F and G, Circ_0011298 and miR‐486‐3p enrichment were determined by RIP assay in Taxol‐resistant NSCLC cells. H, Detection of miR‐486‐3p level in Taxol‐resistant NSCLC cells and parental cells. I, MiR‐486‐3p level was tested in normal, Taxol‐sensitive NSCLC, and Taxol‐resistant NSCLC tissues. J, The correlation between circ_0011298 and miR‐486‐3p in Taxol‐resistant NSCLC tissues was analyzed. K, MiR‐486‐3p level was measured in Taxol‐resistant NSCLC cells introduced with sh‐NC, sh‐circ_0011298#1, sh‐circ_0011298#1+anti‐NC, or sh‐circ_0011298#1+anti‐miR‐486‐3p. *p < 0.05