Skip to main content
. 2019 Aug 7;18(3):732–745. doi: 10.5114/aoms.2019.87205

Figure 7.

Figure 7

Overexpression of circ-RHOJ.1 accelerates the proliferation and inflammatory response and suppresses apoptosis of myocardial cells after I/R injury. A – NRG1 and miR-124-3p expression was evaluated with qRT-PCR assay in circ-RHOJ.1-overexpressing myocardial cells after I/R injury. ***P < 0.001 versus I/R + circ-RHOJ.1 NC group. B – NRG1 expression was measured with western blot assay, and the relative protein expression level of NRG1 was calculated, ***p < 0.001 versus I/R + circ-RHOJ.1 NC group. C – Concentrations of IL-10, IL-2, IL-6, and TNF-α were analyzed with ELISA in circ-RHOJ.1-treated myocardial cells after I/R injury. *P < 0.05, **p < 0.01 versus I/R + NC inhibitor group D – CCK-8 assay was performed to confirm the effect of circ-RHOJ.1 on the viability of myocardial cells after I/R injury, *p < 0.05 versus I/R + circ-RHOJ.1 NC group. E – Effect of circ-RHOJ.1 on the apoptosis rate of myocardial cells after I/R injury, as examined with flow cytometry. **P < 0.01 versus I/R + circ-RHOJ.1 NC group. All the data are presented as mean ± SD (n = 3)