FIGURE 2.

Exploration of the clinical significance of CDCA5. A–F, The Kaplan–Meier survival analyses suggest that the overexpression of CDCA5 exhibits excellent predictive capability in patients >65 years of age (A), both male and female (B), and early stage of Stage (C), T (D), N (E), and M (F), which always predict poor prognosis for patients with LUAD. G, GSEA reveals that several fundamental activities of cells, including cell cycle, base excision repair, DNA replication, mismatch repair, nucleotide excision repair, pyrimidine metabolism, RNA degradation, ubiquitin‐mediated proteolysis, and p53 signaling pathway were enriched in LUAD samples with higher expression of CDCA5. H–I, The expression of PD‐1 (H), and PD‐L1 (I) in LUAD samples with high CDCA5 expression are higher than LUAD samples with low CDCA5 expression