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. 2022 Apr 27;23(9):4819. doi: 10.3390/ijms23094819

Figure 5.

Figure 5

Timeline of the key developments in WGA and milestones of PGT. PGT-A/SR—preimplantation genetic testing for aneuploidies/structural rearrangements; WGA—whole-genome amplification; DOP-PCR—degenerate oligonucleotide primer PCR WGA technique; PEP-PCR—primer extension preamplification PCR WGA technique; MDA—multiple displacement amplification WGA technique; aCGH—array comparative genomic hybridization; MALBAC—multiple annealing and looping-based amplification cycles WGA technique; SNP—single nucleotide polymorphism; NGS—next generation sequencing [2,3,15,20,21,23,26,28,31,32,36,37,38,39,40,41].