TABLE 4.
Biomarker | Expression | Disease‐free survival (months) | p‐value | Overall survival (months) | p‐value |
---|---|---|---|---|---|
PVT1 gene | Low | 48.8 (29.5–68.2) | 0.96 | 69.6 (57.1–82.3) | 0.91 |
High | 49.6 (38.0–61.2) | 73.8 (66.9–80.7) | |||
p53 protein | Low | 39.1 (24.6–53.6) | 0.71 | 55.5 (45.8–65.2) | <0.001 |
High | 51.7 (6.06–39.8) | 80.2 (74.2–86.3) | |||
bcl2 protein | Low | 51.7 (38.4–64.9) | 0.49 | 73.5 (65.2–81.7) | 0.95 |
High | 45.4 (30.9–59.9) | 71.1 (60.8–81.3) | |||
PD−1 protein | Low | 55.5 (39.1–71.9) | 0.58 | 77.7 (71.7–83.6) | 0.28 |
High | 49.3 (37.1–61.5) | 71.5 (62.9–80.1) | |||
PD‐L1 tumor | Low | 50.9 (38.8–63.0) | 0.73 | 79.8(73.6–86.1) | 0.018 |
High | 48.5 (30.1–66.8) | 62.9 (51.7–74.1) | |||
PD‐L1 lymphocyte | Low | 59.7 (45.6–73.7) | 0.08 | 71.9 (62.9–80.9) | 0.63 |
High | 39.6 (26.6–52.5) | 71.9 (64.6–79.1) | |||
BRAF mutation | Negative | 41.9 (28.7–55.1) | 0.11 | 72.2 (65.2–79.3) | 0.92 |
Positive | 57.9 (42.4–73.3) | 73.1 (61.4–84.7) |
Log Rank (Mantel‐Cox) test was used. Data are presented as mean survival estimates in months and 95% confidence interval. Bold values indicate significance at p‐value <0.05.