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Cytotoxic effect of ketamine and norketamine (NK) on RT4 cells. Cells were treated with ketamine (0.01–3 mM) or NK (0.01–0.5 mM) for 24 h, and cell viability was determined using MTT assay. Data are presented as the means ± SD of four independent experiments assayed in triplicate. * p < 0.05 compared to vehicle control.
