Table 5.
Univariate and multivariate linear regression models predicting DBP (mmHg), Group (MAFLD vs. Controls), Beck depression inventory (21 questions), ASQ—global score, and ASQ—somatic assessment, using several dependent variables.
| Dependent Variable | Predictor | B Unadjusted | (95% CI) | p-Value | B Adjusted | (95% CI) | p-Value |
|---|---|---|---|---|---|---|---|
| E/A ratio | DBP (mmHg) * | −0.0274 | (−0.0351−0.0197) | <0.001 | −0.0139 | (−0.0223–−0.0056) | 0.002 |
| GLS—Average | LWASQ—Somatic factor ** | −0.0404 | (−0.0652–−0.0156) | 0.002 | −0.0166 | (−0.0375–0.0043) | 0.124 |
| BDI (21 questions) | Group (MAFLD vs. Controls) *** | 6.0378 | (1.9523–10.1233) | 0.005 | −1.5151 | (−5.3772–2.3469) | 0.445 |
| LWASQ—Global Score | Group (MAFLD vs. Controls) **** | 27.5661 | (5.6326–49.4997) | 0.016 | −10.3165 | (−36.2982–15.6651) | 0.439 |
| LWASQ—Somatic factor | Group (MAFLD vs. Controls) **** | 17.5088 | (5.9149–29.1026) | 0.004 | −7.3504 | (−22.0228–7.322) | 0.33 |
| Interventricular septal wall thickness (mm) | Beck depression inventory (21 questions) ** | 0.0633 | (0.0314–0.0952) | <0.001 | 0.021 | (−0.024–0.0661) | 0.364 |
| Interventricular septal wall thickness (mm) | LWASQ—Global Score ** | 0.0112 | (0.0045–0.018) | 0.002 | 0.0041 | (−0.003–0.0112) | 0.266 |
| Interventricular septal wall thickness (mm) | LWASQ—Somatic factor ** | 0.0223 | (0.0099–0.0346) | <0.001 | 0.0055 | (−0.0076–0.0187) | 0.412 |
* Multivariate linear regression model adjusted for age (years), sex, group (MAFLD vs. controls), body mass index, type 2 diabetes mellitus, systolic blood pressure, Beck depression inventory (21 questions). ** Multivariate linear regression model adjusted for age (years), sex, group (MAFLD vs. controls), body mass index, type 2 diabetes mellitus, systolic blood pressure, diastolic blood pressure. *** Multivariate linear regression model adjusted for age (years), sex, group (MAFLD vs. controls), marital status and education standardized score, comorbidities at high depression risk score, polypharmacy standardized score, antidepressants, smoking dependence and alcohol standardized score. **** Multivariate linear regression model adjusted for age (years), sex, group (MAFLD vs. controls), marital status and education standardized score, comorbidities at high anxiety risk score, polypharmacy standardized score, anxiolytics, smoking dependence and alcohol standardized score. BDI—Beck depression inventory; CI—Confidence interval; DBP—Diastolic blood pressure; E/A ratio—Early diastolic peak velocity/Late diastolic peak velocity; GLS—Global longitudinal strain; LWASQ—Lehrer Woolfolk Anxiety Symptom Questionnaire; MAFLD—Metabolic-associated fatty liver disease.