Table 2.
Pathway enrichment analysis items of 16 LRGs from KEGG
| ONTOLOGY | ID | Description | GeneRatio | BgRatio | P value | P.adjust | qvalue |
|---|---|---|---|---|---|---|---|
| BP | GO:0006641 | triglyceride metabolic process | 10/11 | 105/18670 | 2.23e-22 | 9.62e-20 | 5.50e-20 |
| BP | GO:0006639 | acylglycerol metabolic process | 10/11 | 129/18670 | 1.90e-21 | 2.96e-19 | 1.69e-19 |
| BP | GO:0006638 | neutral lipid metabolic process | 10/11 | 130/18670 | 2.06e-21 | 2.96e-19 | 1.69e-19 |
| BP | GO:0019433 | triglyceride catabolic process | 8/11 | 35/18670 | 1.06e-20 | 1.14e-18 | 6.52e-19 |
| BP | GO:0046461 | neutral lipid catabolic process | 8/11 | 43/18670 | 6.51e-20 | 4.68e-18 | 2.67e-18 |
| MF | GO:0005504 | fatty acid binding | 5/11 | 34/17697 | 8.82e-12 | 3.53e-10 | 1.30e-10 |
| MF | GO:0033293 | monocarboxylic acid binding | 5/11 | 64/17697 | 2.40e-10 | 4.79e-09 | 1.77e-09 |
| MF | GO:0005324 | long-chain fatty acid transporter activity | 3/11 | 11/17697 | 2.94e-08 | 3.92e-07 | 1.44e-07 |
| MF | GO:0031406 | carboxylic acid binding | 5/11 | 193/17697 | 6.42e-08 | 5.18e-07 | 1.91e-07 |
| MF | GO:0036041 | long-chain fatty acid binding | 3/11 | 14/17697 | 6.48e-08 | 5.18e-07 | 1.91e-07 |
| KEGG | hsa03320 | PPAR signaling pathway | 6/9 | 78/8076 | 5.48e-11 | 1.70e-09 | 1.50e-09 |
| KEGG | hsa04975 | Fat digestion and absorption | 2/9 | 43/8076 | 9.74e-04 | 0.015 | 0.013 |
| KEGG | hsa00561 | Glycerolipid metabolism | 2/9 | 61/8076 | 0.002 | 0.020 | 0.018 |
| KEGG | hsa00564 | Glycerophospholipid metabolism | 2/9 | 98/8076 | 0.005 | 0.038 | 0.034 |
| KEGG | hsa04150 | mTOR signaling pathway | 2/9 | 155/8076 | 0.012 | 0.075 | 0.066 |