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. 2022 May 3;11(9):1528. doi: 10.3390/cells11091528

Figure 7.

Figure 7

Mir-143a-3p mediates the KLC2 executed oncogenic phenotype of the LINC00152 ceRNA network. (A) Reduced KLC2 protein levels following miR-143a-3p mimic transfection compared to control in LINC00152 overexpressing cells. (B) MiR-143a-3p overexpression decreased cell viability of HLE cells overexpressing LINC00152. (C) KLC2 knockdown reduced cell viability of LINC00152-overexpressing HLE cells. Data are presented as mean ± SD of at least 3 biological replicates. Welch’s t-test in (A), unpaired t-test in (B) and one-way ANOVA followed by Tukey test in panel (C): * p < 0.05, ** p < 0.01, *** p < 0.001. Abbreviations: siNS, scrambled, nonsense siRNA; siKLC2, siRNA specifically targeting KLC2; LINC00152 OE or LINC OE, LINC00152 overexpression; OE, overexpression; empty, empty vector; rel., relative.