Table 2.
Study characteristics of randomized controlled trials included in the systematic review examining effect of nutrition and physical activity interventions provided by nutrition and exercise practitioners for the general population.
| Trial Name (If Applicable), Author, Year | Country | Setting | Target Population | Mean Age (Years) | Sample Size (Final N) | Duration (Months) | Funding Source | Risk of Bias |
|---|---|---|---|---|---|---|---|---|
|
40-Something Trial Hollis et al. 2015 [46] Williams et al. 2014 [79] Williams et al. 2019 [80] |
Australia | Research/University | Female adults (44–50 years) with healthy weight or overweight (BMI = 18.5–29.9 kg/m2) |
Intervention: 47.6 Control: 46.9 |
40 | 12 | University/Hospital | Low Risk |
| Beleigoli et al. 2020 [35] | Brazil | Research/University | Adults with overweight or obesity (BMI ≥ 25 kg/m2) | Intervention (mean): 33.0 Control: 33.4 |
473 | 6 | Government | High Risk |
| Colleran et al. 2012, [38,39] | United States | Community | Female adults with overweight or obesity (BMI 25–30 kg/m2), postpartum | Intervention: 30.3 Control: 31.9 |
27 | 4 | Government, University/ Hospital |
Low Risk |
|
Finnish DPS Trial Lindstrom et al. 2013 [54] Ruusunen et al. 2012 [72] |
Finland | Outpatient/Primary Care | Adults with type 2 diabetes risk, overweight or obesity (BMI ≥ 25 kg/m2) | Intervention: 55 Control: 55 |
480 | 48 | Government, University/Hospital, Not-for-profit |
Some Concerns |
| Forsyth et al. 2015 [43] | Australia | Outpatient/Primary Care | Adults with anxiety/depression (Mean BMI 31.6 and 31.8 kg/m2 for Intervention and Control) | NR | 94 | 3 | Government | Some Concerns |
|
GHSH Trial Fjeldsoe et al. 2016 [42] Fjeldsoe et al. 2019 [41] |
Australia | Community | Adults (Mean BMI 29.5 kg/m2) | Intervention: 55.5 Control: 51.2 |
211 | 6 | Government, University/Hospital | High Risk |
| Johnson et al. 2019 [50] | United States | Research/University | Adults with obesity (BMI ≥ 30 kg/m2) | Intervention: 42.2 Control: 44.5 |
20 | 3 | Government, Industry | Some Concerns |
| Kennedy et al. 2015 [51] | United States | Community | Adults identified as African American (BMI ≥ 23 kg/m2) | Intervention: 54 Control: 54 |
37 | 12 | Not-for-profit | Some Concerns |
|
LEVA in Real Life Trial Huseinovic et al. 2016 [47] Huseinovic et al. 2018 [48] |
Sweden | Outpatient/Primary Care | Female adults with overweight or obesity (BMI ≥ 27 kg/m2), postpartum | Intervention: 31.8 Control: 32.6 |
89 | 3 | Government, Not-for-profit | Some Concerns |
| Maddison et al. 2019 [56] | New Zealand | Community | Male adults with overweight or obesity (BMI ≥ 25 kg/m2) | Intervention: 40.6 Control: 44.7 |
80 | 4 | NR | Some Concerns |
| Maruyama et al. 2010 [57] | Japan | Community | Adults (Mean BMI 25.7 and 25.8 for Intervention and Control) | Intervention: 43.1, 7.7 Control: 35.5, 8.1 |
87 | 4 | Not-for-profit | Low Risk |
|
MEDIM Trial Siddiqui et al. 2017 [73] Siddiqui et al. 2018 [74] |
Sweden | Research/University | Adults with type 2 diabetes risk, overweight or obesity (BMI ≥ 28 kg/m2) | Intervention: 47.9 Control: 48.9 |
67 | 4 | Industry, University/Hospital | Some Concerns |
| Miller et al. 2015 [59] | United States | Research/University | Adults with type 2 diabetes risk (no information on BMI) | Intervention: 51.6 Control: 50.8 |
68 | 4 | Government | Some Concerns |
| Neale et al. 2017 [60] | Australia | Community | Adults with overweight or obesity (BMI ≥ 25–40 kg/m2) | Intervention: 43.79 Control: 42.10 |
189 | 12 | Industry, Government, Not-for-profit | High Risk |
|
NEW Trial Abbenhardt et al. 2013 [33] Campbell et al. 2012 [37] Duggan et al. 2016 [40] Foster-Schubert et al. 2012 [44] Imayama et al. 2011 [49] Mason et al. 2011 [58] |
United States | Research/University | Female adults with overweight or obesity (BMI ≥ 25 kg/m2) | Intervention: 58.0 Control: 57.4 |
188 | 12 | Government | Some Concerns |
| Nicklas et al. 2014 [61] | United States | Community | Female adults with type 2 diabetes risk, postpartum (Mean BMI 31.2 and 31.6 kg/m2 in the Intervention and Control groups) | Intervention: 33.6 Control: 33.3 |
71 | 12 | Government | Some Concerns |
| Pablos et al. 2017 [62] | Italy | Research/University | Adults with overweight or obesity (BMI ≥ 25 kg/m2) | Intervention: 49.80 Control: 51.25 |
68 | 8 | University/Hospital | Some Concerns |
| Perri et al. 2020 [65] | United States | Community | Adults with obesity (BMI 35–40 kg/m2) | Intervention: 55.9 (individual counseling) and 55.4 (group counseling) Control: 54.8 |
260 | 6 | Government | Some Concerns |
|
RAINBOW Trial Ma et al. 2019 [55] Rosas et al. 2021 [68] |
United States | Outpatient/Primary Care | Adults with overweight or obesity (BMI ≥ 30 kg/m2 or ≥27 kg/m2 if Asian) | Intervention: 50.9 Control: 51.0 |
371 | 12 | Government | Low Risk |
| Rich-Edwards et al. 2019 [66] | United States | Community | Adults, postpartum (BMI ≥ 18.5–40 kg/m2) | Intervention: 30.5 Control: 31.7 |
139 | 9 | Government | Low Risk |
| Rollo et al. 2020 [67] | Australia | Community | Female adults with risk of type 2 diabetes, overweight or obesity (BMI ≥ 18.5–50 kg/m2), postpartum | Intervention: 34.0 Control: 33.6 |
23 | 6 | Not-for-profit | Some Concerns |
| Rosas et al. 2020 [69] | United States | Outpatient/Primary Care | Adults with overweight or obesity (BMI ≥ 24 kg/m2) | Intervention: 50.3 Control: 50.1 |
183 | 12 | Government | Some Concerns |
| Roumen et al. 2011 [70] | Netherlands | Research/University | Adults with type 2 diabetes risk (Mean BMI 29.9 kg/m2 and 29.7 kg/m2 for Intervention and Control groups) | Intervention: 55.0 Control: 58.8 |
109 | 48 | Government, Not-for-profit | Some Concerns |
| Rubinstein et al. 2016 [71] | Argentina, Guatemala, Peru | Community | Adults with pre-hypertension (Mean BMI 30.2 kg/m2 and 30.8 kg/m2 for Intervention and Control groups) | Intervention: 48.6 Control: 43.2 |
553 | 12 | Government, Industry | Some Concerns |
|
Shape Trial Bennett et al. 2013 [36] Krishnan et al. 2019 [52] |
United States | Outpatient/Primary Care | Female adults with overweight or obesity (BMI 25–34.9 kg/m2) | Intervention: 35.6 Control: 35.2 |
177 | 12 | Government | Some Concerns |
| Thomas et al. 2019 [75] | United States | Research/University | Adults with overweight or obesity (BMI 25–45 kg/m2) | NR | 125 | 18 | Government | Some Concerns |
| Toji et al. 2012 [76] | Japan | Community | Adults with overweight or obesity (BMI 24–28 kg/m2) | Intervention: 61 Control: 62 |
32 | 6 | Government | Some Concerns |
|
TXT2BFiT Trial Allman-Farinelli et al. 2016 [34] Partridge et al. 2015 [63] Partridge et al. 2016 [64] |
Australia | Telehealth | Adults at risk of weight gain (BMI 23–32 kg/m2) | 18–35 | 248 | 9 | Government, Not-for-profit | Low Risk |
| Viester et al. 2018 [77] | Netherlands | Workplace | Male adults (Mean BMI 27.4 kg/m2) | Intervention: 46.3 Control: 47.0 |
277 | 6 | Foundation | Some Concerns |
| Weinhold et al. 2015 [78] | United States | Workplace, Research/University | Adults with type 2 diabetes risk, overweight or obesity (BMI 25–50 kg/m2) | Intervention: 51.6 Control: 51.0 |
67 | 4 | Government | Some Concerns |
|
WOMAN Trial Gabriel et al. 2011 [45] Kuller et al. 2012 [53] |
United States | Research/University | Female adults with overweight or obesity (BMI 25–39.9 kg/m2) | Intervention: 56.9 Control: 57.1 |
400 | 36 | Government | Some Concerns |
BMI = body mass index; NR = not reported.