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. 2022 Apr 20;23(9):4568. doi: 10.3390/ijms23094568

Figure 5.

Figure 5

The 15 BACE1 substrates were Alzheimer’s disease (AD)-specific when compared against other diseases. (a) Venn diagram overlaying 25 BACE1 substrates differentially expressed (DE) in AD with proteins DE in traumatic brain injury (TBI), epilepsy, stroke, and experimental autoimmune encephalitis (EAE) (50)). (b,c) Terms from various databases when the 15 AD-specific BACE1 substrates were input into Enrichr, showing log of adjusted p-value. (d) String analysis of the 15 AD-specific BACE1 substrates, showing associations with GO terms.