Table 4.

Univariate and multivariate analysis in elderly patients with gastric cancer for OS

Variable	Univariate analysis			Multivariate analysis
	Hazard ratio	95% CI	p value	Hazard ratio	95% CI	p value
Age (≥80 vs < 80 years)	2.132	1.542–2.947	< 0.001	1.673	1.196–2.340	0.003
Sex (female vs male)	0.944	0.682–1.307	0.728
BMI (< 22.0 vs ≥22.0 kg/m2)	1.211	0.895–1.637	0.214
ASA-PS score (2.3 vs 1)	1.843	0.993–3.423	0.053
Histology (undifferentiated vs differentiated)	1.606	1.183–2.180	0.002	1.362	0.996–1.864	0.053
Lymphatic invasion (present vs absent)	2.326	1.657–3.266	< 0.001	0.900	0.552–1.466	0.671
Venous invasion (present vs absent)	2.007	1.475–2.732	< 0.001	1.364	0.928–2.005	0.114
pT (≥2 vs 1)	2.698	1.973–3.691	< 0.001	1.278	0.867–1.883	0.215
pN (present vs absent)	3.101	2.287–4.205	< 0.001	2.123	1.465–3.079	< 0.001
Operation duration (≥154 vs < 154 min)	1.054	0.571–1.946	0.866
Bleeding (≥206 vs < 206 mL)	1.903	1.407–2.572	< 0.001	1.572	1.151–2.147	0.008
GNRI (< 97.0 vs ≥97.0)	2.454	1.799–3.348	< 0.001	1.905	1.374–2.641	< 0.001

ASA-PS American Society of Anesthesiologists physical status, BMI body mass index, CI confidence interval, GNRI geriatric nutritional risk index, OS overall survival, pT pathological depth of invasion, pN pathological lymph node metastasis