Table 1.
Bacteria species | Cell types | Infection conditions | Effect on cell migration | Ref |
---|---|---|---|---|
P. gingivalis ATCC 33277 | human immortalized oral epithelial cells (HIOECs) | MOI=1, 24 h repeatedly in 5, 10, 15, and 23 weeks |
promote | (Geng et al., 2017) |
primary human oral epithelial cells (OECs) | MOI=10 and 100, 120 h | promote | (Lee et al., 2017) | |
primary gingival keratinocytes | MOI=10, 24 h | inhibit | (Bhattacharya et al., 2014) | |
Human telomerase immortalized gingival keratinocytes (TIGK) | MOI=100,1 h, followed by 23 h in fresh medium | promote | (Fitzsimonds et al., 2021) | |
TIGK | MOI=100, 24 h | promote | (Ohshima et al., 2019) | |
Human immortalized oral keratinocyte cell line OKF6/hTERT-1 | MOI=100, 24 h | promote | (Hoppe et al., 2019) | |
human OSCC cell lines, UM-SCC-14A (floor of mouth) and HSC-3 (tongue) | MOI=10,50,100,2 h | promote | (Kamarajan et al., 2020) | |
SAS and Ca9-22 cells | MOI=1, 24 h | promote | (Inaba et al., 2014) | |
OSC-20 and SAS cells | MOI=100,3 h | promote | (Ha et al., 2016) | |
Human esophageal cancer cell lines NE6-T, KYSE-30 and KYSE-150 | MOI=10, 48 h | promote | (Liang et al., 2020; Qi et al., 2020) | |
secreted gingipains of P. gingivalis ATCC33277 |
human embryonic microglia clone 3 (HMC3) cell line | MOI=1,12 h | promote | (Nonaka and Nakanishi, 2020) |
Outer membrane vesicles (OMVs) of P. gingivalis ATCC 33277 | OSCC cell line (HSC-3) | 6 h | promote | (Liu et al., 2021b) |
Ltp1 of P. gingivalis ATCC 33277 | TIGK | MOI=100, 6 h | promote | (Liu et al., 2021a) |
Heat-killed P. gingivalis ATCC 33277 | OSCC cell line(H400) | MOI=100, 8 d | promote | (Abdulkareem et al., 2018a) |
P. gingivalis W83 | human buccal epithelial cell line HO-1-N-1 | MOI=10,100, 17 h | inhibit | (Laheij et al., 2013) |
heat-killed P. gingivalis W83 | human buccal epithelial cell line HO-1-N-1 | MOI=100, 1000,17 h | inhibit | (Laheij et al., 2013) |
conditioned medium from P. gingivalis W83 | human buccal epithelial cell line HO-1-N-1 | MOI=100,17 h | inhibit | (Laheij et al., 2013) |
P. gingivalis strain 381 | Ca9-22 OSCC cells | MOI=100, 2 h | promote | (Ha et al., 2015) |
F. nucleatum ATCC 25586 | primary gingival keratinocytes | MOI=10:1, 24 h | inhibit | (Bhattacharya et al., 2014) |
human OSCC cell lines, UM-SCC-14A (floor of mouth) and HSC-3 (tongue) | MOI=10,50,100,2 h | promote | (Kamarajan et al., 2020) | |
Colorectal cancer cell lines (HCT-116, LoVo) | MOI=100, 12 h and 24 h | promote | (Chen et al., 2020; Xu et al., 2021a) | |
Heat-killed F. nucleatum ATCC 10953 | OSCC cell line(H400) | MOI=100, 8 d | promote | (Abdulkareem et al., 2018a) |
OSCC cell line(HOC621 cells) | MOI=10, 3 h | promote | (Shao et al., 2021) | |
Heat-killed F. nucleatum JCM8532 | OSCC cell line(HOC621 cells) | MOI=10, 3 h | promote | (Shao et al., 2021) |
Live or heat-killed F. nucleatum JCM11024 | OSCC cell line(HOC621 cells) | MOI=10, 3 h | promote | (Shao et al., 2021) |
Live or heat-killed F. nucleatum ATCC23726 | OSCC cell line(HOC621 cells) | MOI=10, 3 h | promote | (Shao et al., 2021) |
T. denticola ATCC35405 | human OSCC cell lines, UM-SCC-14A (floor of mouth) and HSC-3 (tongue) | MOI=10,50,100,2 h | promote | (Kamarajan et al., 2020) |
P. intermedia ATCC 25611 T. forsythia ATCC 43037 Conditioned medium from Streptococcus mitis LMG 14557 (MOI 100, 1000) and heat-killed Streptococcus mitis LMG 14557 Conditioned medium from Prevotella nigrescens ATCC 33563((MOI=100,1000) heat-killed Prevotella nigrescens ATCC 33563 (MOI 10, 100, 1000) Heat-killed Prevotella intermedia ATCC 25611 (MOI 100, 1000) Tannerella forsythia ATCC 43037 (MOI 50, 500) |
human buccal epithelial cell line HO-1-N-1 | MOI=10,100 or 1000, 17 h | inhibit | (Laheij et al., 2013) |
Periodontal pathogens Porphyromonas gingivalis and Fusobacterium nucleatum promote tumor progression in an oral-specific chemical carcinogenesis model.