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. 2022 Apr 29;13:857400. doi: 10.3389/fimmu.2022.857400

Table 3.

Multivariable Cox regression analysis for TRM.

Risk factors P value HR 95% CI for HR
Low IL22 (n = 41) 0.007 2.72 1.32 – 5.61
Grade 2-4 GI-GvHD (n = 25) 0.010 3.12 1.32 – 7.39
Patient’s age (> 50 years, n = 75) 0.140 1.93 0.80 – 4.66
Steroid (n = 59) 0.170 1.81 0.77 – 4.26
Broad spectrum antibiotics (n = 48) 0.340 1.40 0.71 – 2.78
Conditioning (Standard, n = 13) 0.470 1.41 0.55 – 3.61
Donor (MUD, n = 68) 0.750 0.88 0.42 – 1.88
Stage of underlying disease (advanced, n = 37) 0.750 1.13 0.53 – 2.40
Time of recent SCT to biopsy 0.970 1.00 1.00 – 1.00

A total of 110 patients were analyzed. High-risk groups with respective numbers are indicated for categorical variables. HR, hazard ratio; CI, confidence interval; MUD, matched unrelated donor.