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. 2022 Mar 1;21(11):1194–1211. doi: 10.1080/15384101.2022.2044137

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Figure 1. — CircRNA_0085315 is highly expressed in CC tissues and closely related to survival status of CC patients.

The structure of hsa_circ_0085315 was shown in (A) based on the Cancer-Specific CircRNA Database (CSCD) database. (B) Relative circ_0085315 expression in CC tumor tissues compared with adjacent normal tissues (n = 43) by qRT-PCR analysis. (C) Relative circ_0085315 expression in CC cell lines compared with HCoEpic by qRT-PCR analysis. (D and E) qRT-PCR helped to determine circ_0085315 expression after RNase R treatment in CC cell line. (F) Nuclear RNA fractionation and cytoplasmic experiments analysis of circ_0085315ʹs location in CC cells. (G) The overall survival (OS) probability of CC patients with low- and high-circRNA_0085315 expression (**P < 0.01). CC, colon cancer.