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. 2022 Apr 20;23(9):4557. doi: 10.3390/ijms23094557

Figure 6.

Figure 6

Human immunoglobulin G (IgG) partially depletes3,4-dideoxyglucosone-3-ene (3,4-DGE) from the model solution and, therefore, disables its interconversion to 3-deoxyglucosone (3-DG) and 3-deoxygalactosone (3-DGal). 3,4-DGE (166.2 µM, containing 2.8 µM 3-DG and 9.5 µM 3-DGal) was incubated for 48 h at 37 °C in the absence (blue curve) or presence (orange curve) of IgG (11.5 mg/mL). The time-course curves for the concentrations (in µM, mean ± SD) of (a) 3,4-DGE, (b) 3-DG, and (c) 3-DGal are shown. All experiments were performed in triplicates. Significant differences between the samples with and without IgG are marked (* p < 0.05, ** p < 0.01, *** p < 0.001).