Table 1.
Differentially abundant salivary proteins between horses with equine gastric ulcer syndrome (EGUS) (n = 12) and control group (n = 10). Columns indicate the accession number obtained from UniProt database, protein name, mean and SD abundances of control and EGUS group, Log2(FC) between EGUS and control groups, and p-value derived from Mann–Whitney analysis.
| Accession (UniProt) | Protein Name | Mean and SD Control | Mean and SD EGUS | Log2(FC) | p-Value | Regulation in EGUS |
|---|---|---|---|---|---|---|
| F6QSG9 | Transmembrane protease serine | 0.63 ± 0.39 | 1.32 ± 0.79 | 1.04 | 0.003 | UP |
| A0A3Q2I4F4 | WD repeat domain 1 | 0.45 ± 0.27 | 0.79 ± 0.40 | 0.79 | 0.029 | UP |
| F6YDZ0 | Serpin B5 | 0.61 ± 0.39 | 1.06 ± 0.51 | 0.79 | 0.030 | UP |
| F6W039 | Rho GDP dissociation inhibitor alpha | 0.59 ± 0.41 | 0.950.39 | 0.69 | 0.041 | UP |
| P00559 | Phosphoglycerate kinase 1 | 0.60 ± 0.38 | 0.94 ± 0.42 | 0.65 | 0.041 | UP |
| F6Q818 | Arachidonate 15-lipoxygenase type B | 0.66 ± 0.35 | 1.02 ± 0.41 | 0.62 | 0.019 | UP |
| F6SG30 | Protein S100-A9 | 1.03 ± 0.38 | 1.560.46 | 0.60 | 0.006 | UP |
| F7DMA1 | Carboxypeptidase M | 0.69 ± 0.32 | 1.02 ± 0.29 | 0.57 | 0.013 | UP |
| F6YA47 | Alpha-2-macroglobulin like 1 | 0.88 ± 0.40 | 1.31 ± 0.36 | 0.57 | 0.018 | UP |
| A0A0B4J1C4 | Joining chain of multimeric IgA and IgM | 0.82 ± 0.16 | 1.20 ± 0.51 | 0.54 | 0.021 | UP |
| F6T8J7 | LY6/PLAUR domain containing 3 | 0.90 ± 0.25 | 1.31 ± 0.31 | 0.54 | 0.004 | UP |
| F6WR95 | Sulfhydryl oxidase | 0.91 ± 0.20 | 1.29 ± 0.19 | 0.51 | 0.001 | UP |
| F6SP02 | 14-3-3 protein theta | 0.85 ± 0.34 | 1.21 ± 0.43 | 0.50 | 0.047 | UP |
| A0A5F5PSG4 | Desmoglein 2 | 0.95 ± 0.34 | 1.30 ± 0.36 | 0.46 | 0.047 | UP |
| A0A3Q2KJH8 | Desmocollin 2 | 1.03 ± 0.37 | 1.42 ± 0.36 | 0.45 | 0.023 | UP |
| F6S6J4 | Peroxiredoxin-1 | 0.88 ± 0.48 | 1.19 ± 0.35 | 0.43 | 0.041 | UP |
| A0A5F5PRI0 | Nucleoside diphosphate kinase | 0.86 ± 0.42 | 1.14 ± 0.44 | 0.40 | 0.041 | UP |
| Q28372 | Gelsolin | 0.79 ± 0.30 | 1.04 ± 0.27 | 0.39 | 0.018 | UP |
| F7DW69 | Heat shock 70 kDa protein 1A | 0.94 ± 0.31 | 1.23 ± 0.36 | 0.38 | 0.041 | UP |
| A0A3Q2GYE5 | Kallikrein related peptidase 12 | 0.85 ± 0.31 | 1.09 ± 0.34 | 0.36 | 0.041 | UP |
| A0A3Q2LCR2 | Glucose-6-phosphate isomerase | 0.88 ± 0.24 | 1.13 ± 0.28 | 0.36 | 0.047 | UP |
| A0A5S7NAP8 | Chloride channel accessory 2 | 0.97 ± 0.24 | 1.23 ± 0.30 | 0.35 | 0.035 | UP |
| A0A3Q2HWQ6 | C3-beta-c | 0.89 ± 0.32 | 1.10 ± 0.27 | 0.30 | 0.041 | UP |
| F6PH38 | Fibrinogen beta chain | 0.87 ± 0.21 | 1.07 ± 0.26 | 0.30 | 0.041 | UP |
| A0A5F5PF02 | Tropomyosin alpha-4 chain | 0.93 ± 0.25 | 1.14 ± 0.23 | 0.29 | 0.041 | UP |
| Q4AEE3 | Deoxyribonuclease-1 | 0.98 ± 0.26 | 0.79 ± 0.28 | −0.31 | 0.035 | DOWN |
| F7C450 | Alpha-2-HS-glycoprotein | 1.33 ± 0.60 | 0.91 ± 0.35 | −0.54 | 0.041 | DOWN |
| A0A3Q2I8J7 | Jacalin-type lectin domain-containing protein | 1.19 ± 0.45 | 0.79 ± 0.36 | −0.58 | 0.030 | DOWN |
| F7D917 | 6-phosphogluconate dehydrogenase decarboxylating | 1.12 ± 0.75 | 0.55 ± 0.25 | −1.03 | 0.007 | DOWN |
SD: standard deviation; EGUS: equine gastric ulcer syndrome; FC: fold change.