Table 5.
Differentially abundant serum proteins between horses with equine gastric ulcer syndrome (EGUS) (n = 12) and controls (n = 10). Columns indicate the accession number obtained from UniProt database, protein name, mean and SD abundances of control and EGUS groups, Log2(FC) between EGUS and control groups, and p-value derived from Mann–Whitney analysis.
| Accession (UniProt) | Protein Name | Mean and SD Control | Mean and SD EGUS | Log2(FC) | p-Value | Regulation in EGUS |
|---|---|---|---|---|---|---|
| A0A3Q2HTG2 | Fibrinogen alpha chain | 0.90 ± 0.08 | 1.20 ± 0.54 | 0.42 | 0.022 | UP |
| F7APU2 | Complement factor I | 0.98 ± 0.07 | 1.13 ± 0.30 | 0.20 | 0.049 | UP |
| F6PPQ0 | C3/C5 convertase | 0.94 ± 0.07 | 1.08 ± 0.06 | 0.19 | 0.006 | UP |
| F7DRS2 | Serpin family A member 6 | 0.97 ± 0.08 | 1.08 ± 0.11 | 0.15 | 0.024 | UP |
| A0A3Q2I8Y6 | Alpha-2-glycoprotein 1 zinc-binding | 0.99 ± 0.06 | 1.05 ± 0.07 | 0.08 | 0.036 | UP |
| A0A3Q2LBD1 | Complement component 8 subunit beta | 1.01 ± 0.05 | 0.91 ± 0.06 | −0.14 | 0.000 | DOWN |
| F6REX3 | Pregnancy zone protein | 1.11 ± 0.36 | 0.85 ± 0.23 | −0.39 | 0.042 | DOWN |
SD: standard deviation; EGUS: equine gastric ulcer syndrome; FC: fold change.