Table 6.
Differentially abundant serum proteins between horses with equine glandular gastric disease (n = 6) and controls (n = 10). Columns indicate the accession number obtained from UniProt database, protein name, mean and SD abundances of control and EGGD groups, Log2(FC) between EGGD and control groups, and p-value derived from Kruskal–Wallis analysis.
| Accession (UniProt) | Protein Name | Mean Control | Mean EGGD | Log2(FC) | p-Value | Regulation in EGGD |
|---|---|---|---|---|---|---|
| A0A3Q2HTG2 | Fibrinogen alpha chain | 1.09 ± 0.08 | 0.90 ± 0.23 | 0.29 | 0.029 | UP |
| F6PPQ0 | C3/C5 convertase | 1.08 ± 0.07 | 0.94 ± 0.07 | 0.19 | 0.005 | UP |
| F6VZ73 | Hyaluronan binding protein 2 | 1.05 ± 0.09 | 0.95 ± 0.10 | 0.14 | 0.046 | UP |
| F6PKE1 | Inhibitor of carbonic anhydrase | 1.05 ± 0.05 | 0.98 ± 0.06 | 0.09 | 0.041 | UP |
| F6ZR63 | Complement factor H | 0.87 ± 0.04 | 0.95 ± 0.06 | −0.11 | 0.029 | DOWN |
| A0A3Q2LBD1 | Complement component 8 subunit beta | 0.93 ± 0.05 | 1.01 ± 0.03 | −0.12 | 0.004 | DOWN |
| Q95M34 | Immunoglobulin gamma 1 heavy chain constant region (Fragment) | 0.87 ± 0.10 | 0.99 ± 0.07 | −0.19 | 0.013 | DOWN |
| F7BUV8 | Adiponectin A | 0.96 ± 0.17 | 1.12 ± 0.08 | −0.22 | 0.046 | DOWN |
| F6Z5L1 | Complement subcomponent C1r | 0.69 ± 0.32 | 0.92 ± 0.31 | −0.43 | 0.037 | DOWN |
| F6REX3 | Pregnancy zone protein | 0.82 ± 0.36 | 1.11 ± 0.16 | −0.44 | 0.046 | DOWN |
SD: standard deviation; EGGD: equine glandular gastric disease; FC: fold change.