Table 8.
Differentially abundant serum proteins between horses with equine squamous gastric disease (ESGD) (n = 6) and equine glandular gastric disease (EGGD) (n = 6). Columns indicate the accession number obtained from UniProt database, protein name, mean and SD abundances of EGGD and ESGD groups, Log2(FC) between ESGD and EGGD groups, and p-value derived from Kruskal–Wallis analysis.
Accession (UniProt) | Protein Name | Mean EGGD | Mean ESGD | Log2(FC) | p-Value | Regulation in EGSD |
---|---|---|---|---|---|---|
F6Z5L1 | Complement subcomponent C1r | 0.68 ± 0.29 | 0.93 ± 0.31 | 0.44 | 0.041 | UP |
A0A3Q2KTQ9 | Actin cytoplasmic 1 | 0.87 ± 0.11 | 1.14 ± 0.19 | 0.38 | 0.041 | UP |
F6PVG3 | EGF containing fibulin extracellular matrix protein 1 | 0.92 ± 0.11 | 1.14 ± 0.16 | 0.30 | 0.041 | UP |
F7CSL8 | Alpha-1-antiproteinase 2-like | 0.94 ± 0.15 | 1.12 ± 0.12 | 0.24 | 0.041 | UP |
Q95M34 | Immunoglobulin gamma 1 heavy chain constant region (Fragment) | 0.86 ± 0.07 | 0.99 ± 0.08 | 0.19 | 0.028 | UP |
F7BUV8 | Adiponectin A | 0.96 ± 0.08 | 1.06 ± 0.08 | 0.15 | 0.041 | UP |
F6ZR63 | Complement factor H | 0.87 ± 0.06 | 0.95 ± 0.04 | 0.11 | 0.028 | UP |
F7C450 | Alpha-2-HS-glycoprotein | 0.95 ± 0.11 | 0.85 ± 0.08 | −0.16 | 0.040 | DOWN |
SD: standard deviation; EGGD: equine glandular gastric disease; ESGD: equine squamous gastric disease; FC: fold change.