Table 3.

Relative frequencies and connectivity of the upregulated genes that most contributed to PCA’s first, second, and third components.

	PCA						H Class			L Class
Gene	PC1	PC2	PC3	% Tot Var 1	% Capt Var 2	Cnx 3	n 4	Norm Cnt 5	Norm Cnx 6	n	Norm Cnt	Norm Cnx
GRB2	86.39 7	0.72	1.49	41.49	46.70	753	54	0.43	325.3	36	0.27	200.8
CTNNB1	0.01	41.47	14.02	11.83	13.31	444	81	0.65	287.7	62	0.46	203.9
SKP1	3.03	15.78	7.07	6.27	7.06	234	63	0.50	117.9	25	0.19	43.3
CSNK2A1	0.37	10.38	9.85	4.36	4.91	284	70	0.56	159.0	24	0.18	50.5
PRKDC	0.10	4.50	9.21	2.82	3.17	110	66	0.53	58.1	19	0.14	15.5
HDAC1	1.97	4.09	4.17	2.64	2.98	257	39	0.31	80.2	22	0.16	41.9
YWHAZ	0.72	1.52	7.38	2.10	2.37	522	109	0.87	455.2	67	0.50	259.1
YWHAB	1.04	0.96	3.22	1.33	1.50	310	83	0.66	205.8	33	0.24	75.78
PSMD2	0.14	2.23	3.78	1.29	1.45	132	53	0.42	56.0	NA 8	NA	NA
EGFR	0.18	4.43	0.35	1.12	1.27	464	56	0.45	207.9	43	0.32	147.8
Total	93.95	86.08	60.54	75.25	84.72	–	674	–	1953.1	331	–	1038.5

¹ Percentage of total variance. ² Percentage of captured variance. ³ Connection number. ⁴ Sample number. ⁵ Normalized counts. ⁶ Normalized connections. ⁷ The numbers for PC1, PC2, and PC3 represent the gene contributions (%) to their respective components. ⁸ NA is for: not available. The deep gray backgrounds represent relative frequencies larger than 5%, and the bold underlined numbers represent those between 1% and 5%.