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. 2022 Apr 27;23(9):4827. doi: 10.3390/ijms23094827

Scheme 6.

Scheme 6

Reagents and conditions: (a) K2CO3, dry DMF, r.t., 30’; then phenethyl bromide, 80 °C, 4 h; (b) NaOH 6N, EtOH 96%, reflux, 4 h; HCl 6N (c) K2CO3, dry DMF, r.t., 30’; then benzyl bromide, 80 °C, 4 h.