Table 3.
Modulation of expression of genes involved in antigen processing and presentation (APP) MHC class I and II pathways and autophagy during vaccination of teleost fish species.
| Vaccine 1 | Host Species | MHC I 2 APP | MHC II 2 APP | Autophagy 2 | Organ or Cell | Reference |
|---|---|---|---|---|---|---|
| Vibrio harvey | Cynoglossus semilaevis | n.d. | + | n.d. | Kidney. | [61] |
| Edwardsiella tarda | Danio rerio | + | − | n.d. | Liver and spleen. | [135,136] |
| Vibrio anguillarum and Edwardsiella tarda | Scophthalmus maximus | + | + | n.d. | Liver and spleen, kidney. | [137] |
| Danio rerio | + | + | n.d. | Liver and spleen. | [137] | |
| Vibrio parahaemolyticus, Vibrio alginolyticus and Aeromonas hydrophila | Larimichthys crocea | + | + | n.d. | Spleen. | [138] |
| VHSV | Danio rerio | n.d. | n.d. | + | Fibroblast cell line and muscle. | [139] |
| SVCV | Danio rerio | n.d. | n.d. | + | Fibroblast cell line and muscle. | [139] |
1 Vaccines addressed to the indicated pathogens. Spring viremia of carp virus (SVCV), Viral Hemorrhagic Septicemia Virus (VHSV); 2 Expression of genes related to APP MHC class I pathways, APP MHC class II pathways or autophagy were (+) upregulated, (−) downregulated or (n.d.) not determined.