Table 1.
WT (n = 7) |
5xFAD (n = 4) |
APP23 (n = 7) |
p-Value | |
---|---|---|---|---|
Total cMBs | 0 | 0.50 (0–1.75) $ | 6 (4–8)** | <0.001 |
Size (µm) | 0 | 195.91 (48.44–249.25) ** | 231.09 (200.13–261.58) *** | <0.001 |
Volume (mm3) | 0 | 0.01 (0.002–0.015) | 0.01 (0.009–0.016) *** | <0.001 |
Hemorrhagic area (mm2) | 0 | 1.47 (0–7.22) $ | 28.31 (14.68–79.82) ** | <0.01 |
Data are expressed as the median (interquartile range). cMBs, cerebral microbleeds. p-Values < 0.05 are shown in bold. ** p < 0.01 vs. WT; *** p < 0.001 vs. WT; $ p < 0.05 vs. APP23.