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. 2022 May 9;23(9):5259. doi: 10.3390/ijms23095259

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The effect of the overexpression of FXR on angiogenic related protein expression. (A) The expression of VEGFA, signal transducer and activator of transcription 3 (STAT3), phospho-Stat3 (p-STAT3), nitric oxide synthase 2 (NOS2) and hypoxia-inducible factors-1α (HIF-1α) were analyzed by Western blotting in TSGH 8301 and T24 cells after FXR overexpression. GAPDH was used as the loading control. (B) The bar graphs show the relative quantitative analysis of the aforementioned proteins. * p < 0.05; ** p < 0.01 compared with the control group.