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. 2022 Apr 29;11(9):2517. doi: 10.3390/jcm11092517

Table 2.

Clinical variables and mood-stabilizing treatment of participants with BD.

Individuals with BD (n = 48)
Diagnosis Bipolar I: 72.9%
Bipolar II: 27.1%
Years of illness (Mean ± SD) 20.82 (±9.72)
Number of depressions (Mean ± SD) 6.42 (±9.59)
 - Mild 4.71 (±4.66)
 - Moderate 4.87 (±8.93)
 - Severe 1.56 (±2.03)
Number of manic episodes (Mean ± SD) 6.78 (±10.19)
 - Hypomanic 3.42 (±6.10)
 - Moderate manic 2.38 (±4.74)
 - Severe manic 1.13 (±1.85)
CGI (Mean ± SD) 2.53 (±0.91)
HAMD (Mean ± SD) 4.11 (±3.86)
YMRS (Mean ± SD) 1.68 (±2.49)
HAMA (Mean ± SD) 6.21 (±5.14)
Alda Score
Lithium Valproate Lamotrigine
Current prophylactic treatment (n, %) 44 (91.66%)
 - only lithium 8 (16.67%) 2.75 (±2.76)
 - only anticonvulsant 11 (22.92%)
  - only valproate 8 (16.67)% 4.00 (±0.82)
  - only lamotrigine 2 (4.17%) 1.00 (±1.41)
 - only antipsychotic 3 (6.25%)
 - lithium + anticonvulsant 7 (14.58%) 3.86 (±2.79)
  - with valproate 3 (6.25%) 3.67 (±3.21) 3.67 (±3.21)
  - with lamotrigine 2 (4.17%) 5.50 (±2.12) 8 (±0)
 - lithium + antipsychotic 2 (4.17%) 0
 - anticonvulsant + antipsychotic 10 (20.83%)
  - with valproate 7 (14.58%) 2.86 (±2.48)
  - with lamotrigine 1 (2.08%) 7
Other psychopharmaceuticals (n, %)
 - Antipsychotics in subprophylactic dose (n = 44) 17 (38.64%)
 - Antidepressants (n = 44) 11 (25.00%)
 - Benzodiazepines (n = 44) 23 (52.27%)

Note. Abbr.: BD = bipolar disorder; CGI = Clinical Global Impression; HAMA = Hamilton Rating Scale for Anxiety; HAMD = Hamilton Rating Scale for Depression; SD = standard deviation; YMRS = Young Mania Rating Scale.