Multifunctional Modified Chitosan Biopolymers for Dual Applications in Biomedical and Industrial Field: Synthesis and Evaluation of Thermal, Chemical, Morphological, Structural, In Vitro Drug-Release Rate, Swelling and Metal Uptake Studies

. 2022 Apr 30;22(9):3454. doi: 10.3390/s22093454

$A A$	Acrylic acid
$A A m$	Acrylamide
$A N$	Acrylonitrile
$K P S$	Potassium persulfate
$H_{2} O$	Water
$D S$	Diclofenac sodium
$S E M$	Scanning Electron Microscopy
$T G A$	Thermogravimetric analysis
$D T A$	Differential thermal analysis
$C h$	Chitosan
$X R D$	Xray Diffraction
$F T I R$	Fourier Transform Infrared Spectroscopy
$p H$	potential of hydrogen
$I P N$	Interpenetrating polymer network
$s e m i - I P N$	Semi-Interpenetrating polymer network
$5 - F U$	Fluorouracil
$N F D$	nifedipine
$H C l$	Hydrochloride
$N a O H$	Sodium hydroxide
$K H_{2} P O_{4}$	Potassium dihydrogen phosphate
$K C l$	Potassium chloride
$N a_{2} B_{4} O_{7} . 10 H_{2} O$	sodium tetraborate decahydrate (borax)
$F e S O_{4}$	Ferrous sulfate
$P b {(N O_{3})}_{2}$	Lead (II) nitrate
$D M F$	Dimethylformamide
$P_{g}$	Percent grafting
$% G E$	Grafting efficiency
$P_{u}$	Metal ion percent uptake
$K_{d}$	Metal ion partition coefficient
$Q_{r}$	Metal ions retention capacity
$P_{d u}$	Percent drug uptake
$D_{o}$	Total drug taken in solution
$D_{l}$	Drug left in supernatant liquid
$P_{d r}$	Percent drug release
$D_{s}$	Concentration of drug in solution
$- g r a f t -$	Grafting
$- c o p -$	copolymer
$C h - g r a f t - p o l y$ ( $A A - c o p - A A m$ )	Binary graft copolymer of comonomer acrylamide
$C h - g r a f t - p o l y$ ( $A A - c o p - A N$ )	Binary graft copolymer of comonomer acrylonitrile
$L M W$	Low molecular weight