Table 1.

Action mechanism of different phytochemicals of C. papaya against thrombocytopenia.

Bioactive Component	Mechanism of Action	Reference
Carpaine	An alkaloid Stimulates ALOX-12 and PTFAR genes to produce megakaryocytes that mature and release more platelets Stimulates CD110, i.e., a receptor on megakaryocytes results in high platelet production	[13,14]
Quercetin	A flavonoid Decrease platelet destruction by binding viral proteases Inhibit viral replication that ceases platelet destruction by the viruses	[5]
Antioxidants	Ascorbic acid and beta-carotene Stabilize plate membrane Inhibit hemolysis Decrease platelet destruction	[15]